Reference architectures: overview

Last reviewed: 2026-06-28 — see the freshness policy.

Learning objectives

After this chapter you will be able to:

  • Read the case studies in this part as worked, end-to-end SA deliverables.
  • Use a consistent structure to document any reference architecture.
  • Map each case study to the concepts and labs earlier in the bootcamp.

What this part is

Parts 1–8 taught the building blocks. This part puts them together into five worked reference architectures — the kind of artifact an SA produces and defends. Each is a complete solution to a realistic brief, not a feature tour, and each links to a hands-on lab.

How each case study is structured

Every case study follows the same SA deliverable shape — the structure you should reuse for your own designs and the capstone:

  1. Problem & context — the business problem and who has it.
  2. Requirements (NFRs) — the measurable bar (security, latency, availability, compliance, cost).
  3. Architecture — the design, as a C4-style diagram.
  4. Key decisions & trade-offs — the ADRs: what was chosen and what was given up.
  5. Compliance mapping — which controls satisfy which regime.
  6. Cost — the TCO shape.
  7. Lab — where to build it.

The five case studies

flowchart TB FHIR["FHIR interoperability platform<br/>(Parts 2, 3, 8)"] RWD["RWD lakehouse on OMOP<br/>(Parts 2, 3, 5)"] RAG["Clinical RAG assistant<br/>(Parts 3, 4, 6)"] Agent["Agentic AI assistant<br/>(Parts 2, 6)"] Gen["Genomics pipeline<br/>(Parts 3, 4, 7)"]
Case study Brings together Lab
FHIR interoperability platform HL7v2/FHIR, HIPAA, EHR integration hls-fhir-interop
RWD lakehouse OMOP, lakehouse, governance, RWE hls-lakehouse-rwd
Clinical RAG GCP/Vertex, RAG, PHI boundary RAGonGCP
Agentic AI assistant Bedrock agents, tools, guardrails aws-health-agents
Genomics pipeline Sequencing, HealthOmics, variant stores RNASEQ

Read them as exemplars: the value is in why each decision was made and what it traded — that reasoning is the SA craft this bootcamp builds.

Check yourself

  1. What seven sections make up a reference-architecture write-up here, and why does "trade-offs" matter as much as the diagram?
  2. Which earlier parts does the RWD lakehouse case study draw on?
  3. Why are these framed as worked deliverables rather than product tours?

Further reading

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